After the TREAD Act was mandated in 2007, all vehicles manufactured in the United States beginning in 2008, must be installed with direct or indirect TPMS systems.

The Mercedes-Benz E-Class is installed with a direct TPMS system, which means there are TPMS sensors in the wheel. Direct TPMS has TPMS sensors installed in the wheel; if one or more tires indicate low tire pressure, the TPMS sensors will transfer the information to the vehicle’s ECU. An indicator light (low-line TPMS system) or each tire pressure will show on the dash (high-line TPMS system). 

A TPMS relearn is recommended after a sensor replacement or tire rotation. When services are performed, such as a tire change or TPMS sensor replacement, in one or more tires of a Mercedes-Benz E-Class, a TPMS relearn must be performed to transfer the sensor information to the vehicle’s ECU.

Type of TPMS system

• Direct TPMS, sensors are installed in the wheel
• All OE and aftermarket TPMS part numbers and service kit replacement options for the Mercedes C-Class can be found in the VT56, VT36 and most Powered by ATEQ TPMS Tools in “Service TPMS”.

Type of TPMS frequency

• 315 MHz, years 2000-2005
• 433 MHz, years 2010-2019 
• Years 2006-2009 use both 315 MHz and 433 MHz frequencies

Type of Relearn Procedure

• Auto relearn

Type of TPMS tool required for TPMS reset

• TPMS activation tool (VT56, VT55, VT15, VT31, VT36 and most Powered by ATEQ TPMS Tools)

Auto relearn procedure required for TPMS reset

• Confirm TPMS sensors are properly installed
• Adjust tire pressures to placard value
• Activate sensors with TPMS activation tool
• Drive the vehicle for up to 10 minutes

While the video shows a Mercedes-Benz S-Class, the same procedure will work on E-Class vehicles 

Troubleshooting tips

Troubleshooting tips when activating a TPMS sensor on a Mercedes-Benz

• Try deflating the tire by 10 PSI. On some models for the Mercedes-Benz, manufacture years 2000-2006, TPMS sensors may not activate unless pressure drops at least 10 PSI.
• Be sure to hold to the tool above the valve stem on the sidewall of the tire for the most accurate signal reading. Note that some oversized aftermarket wheels may cause signal interference.

• If there are issues activating the sensor, with an error “no signal detected”, the wrong frequency may have been selected on the tool, or the wrong sensor frequency was installed in the wheel.